Carl Fratter Selected Research

Metformin (Glucophage)

10/2015

A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA.

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Carl Fratter Research Topics

Disease

10	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 01/2005
5	Muscular Diseases (Myopathy) 01/2022 - 01/2013
3	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 08/2017 - 12/2014
3	Diffuse Cerebral Sclerosis of Schilder (Alpers' Disease) 01/2016 - 08/2008
2	Mitochondrial Myopathies (Mitochondrial Myopathy) 01/2022 - 01/2017
2	Neuralgia (Stump Neuralgia) 11/2018 - 01/2018
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2018 - 12/2014
2	Liver Diseases (Liver Disease) 12/2016 - 06/2013
1	Pyruvate Dehydrogenase Complex Deficiency Disease 09/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Ataxia (Dyssynergia) 01/2019
1	Diabetic Neuropathies (Diabetic Neuropathy) 11/2018
1	Respiratory Insufficiency (Respiratory Failure) 01/2018
1	Pain (Aches) 01/2018
1	Epilepsy (Aura) 11/2017
1	Optic Nerve Diseases (Optic Neuropathy) 01/2017
1	Optic Atrophy 01/2017
1	Cataract (Cataracts) 01/2017
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2017
1	Deafness (Deaf Mutism) 01/2017
1	Night Blindness (Nyctalopia) 01/2017
1	Acute Liver Failure (Fulminant Hepatic Failure) 12/2016
1	Disease Progression 10/2015
1	Noninsulin-dependent diabetes mellitus with deafness 10/2015
1	Muscle Hypotonia (Hypotonia) 02/2014
1	Status Epilepticus (Complex Partial Status Epilepticus) 06/2013
1	Seizures (Absence Seizure) 06/2013
1	Epilepsia Partialis Continua 06/2013
1	Liver Failure 06/2013
1	Drug Resistant Epilepsy 06/2013
1	Ophthalmoplegia (External Ophthalmoplegia) 01/2013
1	Kearns-Sayre Syndrome 09/2011
1	1 X-linked Charcot-Marie-Tooth disease 07/2010
1	Neoplasms (Cancer) 01/2008

Drug/Important Bio-Agent (IBA)

17	Mitochondrial DNA (mtDNA)IBA 01/2020 - 01/2005
4	DNA (Deoxyribonucleic Acid)IBA 09/2020 - 01/2008
4	Lactic Acid (Lactate)FDA LinkGeneric 01/2020 - 06/2013
3	EnzymesIBA 09/2020 - 01/2005
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
2	DNA Polymerase gammaIBA 01/2016 - 06/2013
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2013 - 11/2012
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2022
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2020
1	LipidsIBA 01/2020
1	Sodium Channels (Sodium Channel)IBA 11/2018
1	Carbamazepine (Tegretol)FDA LinkGeneric 11/2018
1	Analgesics (Analgesic Drugs)IBA 01/2018
1	NAD (NADH)IBA 01/2018
1	ElementsIBA 11/2017
1	Biomarkers (Surrogate Marker)IBA 08/2017
1	CreatinineIBA 08/2017
1	Creatine Kinase (Creatine Phosphokinase)IBA 08/2017
1	fibroblast growth factor 21IBA 08/2017
1	ribonuclease HIIBA 06/2017
1	Lys Transfer RNAIBA 01/2017
1	Retinaldehyde (Retinal)IBA 01/2017
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2015
1	Metformin (Glucophage)FDA LinkGeneric 10/2015
1	Valproic Acid (Depakote)FDA LinkGeneric 06/2013
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 09/2011
1	Gap Junction beta-1 ProteinIBA 07/2010

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 11/2018
1	Therapeutics 01/2018